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Galecto启动抗MutCALR管道候选药物的临床开发
2026-01-12 21:17
- DMR-001, a potentially best-in-class mutant calreticulin ("mutCALR") targeting monoclonal antibody, on track for expected IND submission, or equivalent, in mid-2026 with anticipated first-in-human dosing via subcutaneous administration
- Recent addition of deep hematology/oncology drug development experience with the appointment of a Chief Operating Officer and Chief Medical Officer
- Pipeline of additional candidates advancing to the clinic, with first IND submission of DMR-002 expected in second half of 2026
- Cash balance, following $285M raised in the November PIPE, provides financial runway into 2029 to support multiple data milestones, including Ph1 clinical proof-of-concept data for DMR-001 anticipated in 2027
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